San Diego, California

In addition to being home to a world-class zoo and aquarium, San Diego is a laid-back navy town that is the closest U.S. city to Mexico. Great Mexican/American cuisine, Spanish-inspired architecture and what some consider the best weather in North America, make San Diego a destination unto itself.

Cabo San Lucas, Mexico

This southernmost enclave on the tip of the Baja Peninsula features unearthly rock formations, cantinas owned by rock stars and hundreds of ways to enjoy yourself on, in, under and close to the water. Cabo is also blessed with a coastline that's ideal for kayak exploration, snorkeling, whale-watching or perhaps a romantic rendezvous.

Mazatlan, Mexico

If you can manage to peel yourself off the placid beaches for a short while, you can visit one of the many shops and galleries that dot this island known by many as the "Pearl of the Pacific". To explore the heart of Old Mazatlán put on some comfortable shoes and take your time - everyone else here does. It's one of the most laid-back destinations in Mexico.

Puerto Vallarta, Mexico

A traditional Mexican village inhabited by genuinely warm people, Puerto Vallarta features beautiful beaches, boutique shopping and some of the most picturesque and challenging golf courses in the Western Hemisphere.